Search results for " Hernia"

showing 10 items of 194 documents

Morphogenetically-Active Barrier Membrane for Guided Bone Regeneration, Based on Amorphous Polyphosphate

2017

We describe a novel regeneratively-active barrier membrane which consists of a durable electrospun poly(ε-caprolactone) (PCL) net covered with a morphogenetically-active biohybrid material composed of collagen and inorganic polyphosphate (polyP). The patch-like fibrous collagen structures are decorated with small amorphous polyP nanoparticles (50 nm) formed by precipitation of this energy-rich and enzyme-degradable (alkaline phosphatase) polymer in the presence of calcium ions. The fabricated PCL-polyP/collagen hybrid mats are characterized by advantageous biomechanical properties, such as enhanced flexibility and stretchability with almost unaltered tensile strength of the PCL net. The pol…

0301 basic medicineBone Regenerationcollagen-inducingBarrier membranePolymersPharmaceutical Science02 engineering and technologyMatrix (biology)chemistry.chemical_compoundMiceOsteogenesisPolyphosphatesDrug Discoverystromal cell-derived factor-1Pharmacology Toxicology and Pharmaceutics (miscellaneous)MC3T3-E1 cellsChemistrybiologizationAnatomy3T3 Cells021001 nanoscience & nanotechnology3. Good healthMembranetensile strength/resistanceAlkaline phosphataseCollagen0210 nano-technologyinorganic polyphosphateSurface PropertiesPolyestersArticleAngiopoietin-203 medical and health sciencesCalcification PhysiologicAnimalsHumansBone regenerationTissue EngineeringPolyphosphateMesenchymal stem cellMembrane ProteinsMembranes ArtificialMesenchymal Stem Cellspolypropylene mesh030104 developmental biologyGene Expression RegulationBiophysicsbiologization; hernia repair; inorganic polyphosphate; collagen-inducing; polypropylene mesh; tensile strength/resistance; stromal cell-derived factor-1; MC3T3-E1 cellsNanoparticlesWound healinghernia repairMarine Drugs
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Is laterality of congenital diaphragmatic hernia a reliable prognostic factor? French national cohort study.

2020

International audience; Objectives: The objective of this study was to assess whether the laterality of congenital diaphragmatic hernia (CDH) was a prognostic factor for neonatal survival.Methods : This was a cohort study using the French national database of the Reference Center for Diaphragmatic Hernias. The principal endpoint was survival after hospitalization in intensive care.We made a comparative study between right CDH and left CDH by univariate and multivariate analysis. Terminations and stillbirths were excluded from analyses of neonatal outcomes.Results: A total of 506 CDH were included with 67 (13%) right CDH and 439 left CDH (87%). Rate of survival was 49% for right CDH and 74% …

0301 basic medicineMaleMultivariate analysisSurvival030105 genetics & heredityCohort Studies0302 clinical medicinePregnancyPrenatal DiagnosisInfant MortalityRisk of mortalityAntenatal DiagnosisLungGenetics (clinical)030219 obstetrics & reproductive medicineObstetrics and GynecologyMetaanalysisPrognosis3. Good healthLateralityCardiologyFemaleFranceCohort studyAdultmedicine.medical_specialtyPrognostic factorFetal Lung-VolumeDiaphragmatic breathingOutcomes[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics03 medical and health sciencesIntensive careInternal medicineUltrasoundmedicineHumansMortalityLiver HerniationRetrospective Studies[SDV.GEN]Life Sciences [q-bio]/Geneticsbusiness.industry2 CitiesInfant NewbornCongenital diaphragmatic herniaInfantReproducibility of Resultsmedicine.diseasebusinessPredictionHernias Diaphragmatic CongenitalPrenatal diagnosisREFERENCES
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The consumption of snacks and soft drinks between meals may contribute to the development and to persistence of gastro-esophageal reflux disease

2019

Abstract The hypothesis The habit of snacking and drinking soft beverages between breakfast, lunch and dinner, which is very widespread in the western world, could be a primum movens, thereby contributing to the development and subsequent persistence of gastroesophageal reflux disease (GERD). What does the proposed hypothesis based on? The high prevalence of GERD suggests that it is very probably caused by factors, which are intrinsic and widespread in a western lifestyle. Ingesting snacks or imbibing soft drinks between breakfast, lunch and dinner causes additional gastric acid secretion, acid pocket formation, and additional transient lower esophageal sphincter relaxations (TLESRs) with a…

0301 basic medicinemedicine.medical_specialtyCarbonated BeveragesOverweightGastroenterologyEsophageal Sphincter LowerGastric AcidHiatal hernia03 medical and health sciencesEsophagus0302 clinical medicineRisk FactorsInternal medicinePrevalencemedicineHumansObesityEsophagusLife StyleGastro-esophageal Reflux GERD Lifestyle modifications Transient Lower Esophageal Sphincter Relaxation TLESR Snacking and Soft drinks consumption Hiatal Hernia Overweight ObesitySnackingbusiness.industrydigestive oral and skin physiologyRefluxfood and beveragesFeeding BehaviorGeneral MedicineModels TheoreticalOverweightmedicine.diseaseObesitydigestive system diseasesDietHernia Hiatal030104 developmental biologymedicine.anatomical_structureGastroesophageal RefluxGERDGastric acidSnacksmedicine.symptombusiness030217 neurology & neurosurgery
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Clinical reappraisal of SHORT syndrome withPIK3R1mutations: toward recommendation for molecular testing and management

2015

SHORT syndrome has historically been defined by its acronym: short stature (S), hyperextensibility of joints and/or inguinal hernia (H), ocular depression (O), Rieger abnormality (R) and teething delay (T). More recently several research groups have identified PIK3R1 mutations as responsible for SHORT syndrome. Knowledge of the molecular etiology of SHORT syndrome has permitted a reassessment of the clinical phenotype. The detailed phenotypes of 32 individuals with SHORT syndrome and PIK3R1 mutation, including eight newly ascertained individuals, were studied to fully define the syndrome and the indications for PIK3R1 testing. The major features described in the SHORT acronym were not unive…

0301 basic medicinemedicine.medical_specialtyPediatricsTeethingbusiness.industryIntrauterine growth restrictionmedicine.diseaseShort stature3. Good health03 medical and health sciencesInguinal hernia030104 developmental biologyEndocrinologySHORT syndromeInternal medicineSpeech delayGeneticsEtiologymedicinemedicine.symptombusinessLipoatrophyGenetics (clinical)Clinical Genetics
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Epidemiology of congenital diaphragmatic hernia in Europe: a register-based study.

2015

INTRODUCTION: Published prevalence rates of congenital diaphragmatic hernia (CDH) vary. This study aims to describe the epidemiology of CDH using data from high-quality, population-based registers belonging to the European Surveillance of Congenital Anomalies (EUROCAT).METHODS: Cases of CDH delivered between 1980 and 2009 notified to 31 EUROCAT registers formed the population-based case series. Prevalence over time was estimated using multilevel Poisson regression, and heterogeneity between registers was evaluated from the random component of the intercept.RESULTS: There were 3373 CDH cases reported among 12 155 491 registered births. Of 3131 singleton cases, 353 (10.4%) were associated wit…

ANOMALIESAdultMalePediatricsmedicine.medical_specialtyAUSTRALIAAdolescentPopulationPrevalencePrenatal diagnosisGestational AgeEurope/epidemiologysymbols.namesakeYoung AdultEpidemiologyPrevalenceMedicineBirth WeightHumansMALFORMATIONSAbnormalities MultiplePoisson regressionRegistriesPRENATAL-DIAGNOSISeducationeducation.field_of_studybusiness.industryMORTALITYInfant NewbornObstetrics and GynecologyCongenital diaphragmatic herniaGestational ageGeneral MedicineDEFECTSmedicine.diseaseSurvival AnalysisCongenital anomalies ; Diaphragmal hernia ; Epidemiology ; EuropeEuropeHernias Diaphragmatic Congenital/epidemiologyRelative riskPopulation SurveillancePediatrics Perinatology and Child HealthsymbolsAbnormalities Multiple/epidemiologyFemalebusinessHernias Diaphragmatic CongenitalMaternal AgeArchives of disease in childhood. Fetal and neonatal edition
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Giant pseudocyst of the abdominal wall following incisional ventral hernia repair: an extremely rare clinical entity. Report of a case

2021

Il “gold standard” per il trattamento dei laparoceli è l’intervento chirurgico con impiego di protesi, nonostante questo approccio sia gravato da numerose complicanze post-operatorie; tra queste possiamo annoverare le pseudocisti giganti della parete addominale, tale evenienza risulta ancora molto rara e la sua eziopatogenesi riamane non chiara. In questo lavoro descriviamo il caso clinico di una paziente di 36 anni, diabetica ed obesa, precedentemente sottoposta a taglio cesareo e riparazione di laparocele con posizionamento di protesi in sede soprafasciale. La paziente si è presentata presso i nostri ambulatori per la comparsa di un gonfiore asintomatico a livello della fossa iliaca sinis…

AdultCystsRecurrenceAbdominal WallDiabetes MellitusHumansIncisional HerniaFemaleObesitySurgical MeshAbdominal Wall pathology Adult Cysts* / pathology Diabetes Mellitus Female Hernia Ventral* / surgeryHernia VentralHerniorrhaphy
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Imaging of urinary bladder hernias

2005

Lorenzo E. Bacigalupo1, Michele Bertolotto2, Filippo Barbiera3, Pietro Pavlica4, Roberto Lagalla3, Roberto S. Pozzi Mucelli2, Lorenzo E. Derchi1 Bacigalupo LE, Bertolotte M, Barbiera F, et al. erniation of the urinary bladder is not rare. It is usually considered that 1–3% of all inguinal hernias involve the bladder [1], and Iason [2], in 1944, reported an incidence of 10% in men older than 50 years. Most bladder hernias involve the inguinal and femoral canals, with the latter more frequent in women, and a predilection for the right side has been reported. However, herniations through ischiorectal, obturator, and abdominal wall openings have also been described. Any portion of the bladder m…

AdultDiagnostic ImagingMalemedicine.medical_specialtyHerniaPerforation (oil well)Urologyurologic and male genital diseasesAbdominal wallDiagnosis Differentialurinary bladder herniasScrotummedicineHumansRadiology Nuclear Medicine and imagingHerniaProstatismAgedUrinary bladderbusiness.industryradioiologyUrinary bladder; Urinary bladder hernias; PeritoneumUrinary Bladder DiseasesimagingGeneral MedicineMiddle Agedmedicine.diseaseFemoral herniafemale genital diseases and pregnancy complicationsUrinary bladderradioiology; imaging; urinary bladder herniasSurgeryNeck of urinary bladdermedicine.anatomical_structureFemalePeritoneumbusiness
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Incarcerated hernia in a trocar site following laparoscopic gastric bypass

2013

This paper reports a case of small bowel occlusion due to the herniation of an ileal ansa at the site of the insertion of a 12-mm trocar. A 28-year-old obese female patient underwent laparoscopic surgery for gastric bypass, the skin incisions of the trocar insertion sites were closed with absorbable sutures. Small bowel occlusion occurred on post-operative day 6 and the patient again underwent laparoscopic surgery. Laparoscopic exploration confirmed the suspected presence of the incarcerated hernia of an ileal ansa at the site of the trocar insertion which was freed without any need for bowel resection. The fascial defect was successfully closed under direct vision with the use of a special…

AdultHerniaIleal DiseasesGastric BypaGastric BypassAdult; Female; Gastric Bypass; Hernia; Humans; Ileal Diseases; Intestinal Obstruction; Surgical Instruments; LaparoscopySurgical InstrumentsSurgical InstrumentSettore MED/18 - Chirurgia GeneraleHumansIleal DiseaseFemaleLaparoscopyIntestinal ObstructionHuman
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Inguinal hernioplasty improves the quality of life in patients with cirrhosis.

2008

Abstract Background The optimal management of symptomatic inguinal hernia (SIH) in cirrhotics is still undefined. Both hernia and cirrhosis impair quality of life (QOL). The aim of this study was to evaluate QOL by a Short Form-36 (SF-36) questionnaire in cirrhotic patients undergoing inguinal hernioplasty. Methods Thirty-two cirrhotic patients undergoing inguinal hernioplasty were evaluated. They were classified according to Child's class and to the absence or presence of refractory ascites. The SF-36 questionnaire was administered the day before and 6 months after surgery. Global analyses of the 8 domains of SF-36 and of 2 comprehensive indexes of SF-36, Physical Component Summary (PCS) a…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosismedicine.medical_treatmentHernia InguinalQuality of lifemedicineHumansHerniaIn patientProspective StudiesInguinal hernioplastybusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseHernia repairhumanitiesOptimal managementSurgeryInguinal herniaSymptomatic inguinal hernia (SIH) Quality of life (QOL) Cirrhosis.Quality of LifeSurgerybusiness
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Histological findings in direct inguinal hernia

2013

Abstract BACKGROUND: The study is focused on recognizing the histological changes of the structures close to and around the hernia opening in patients having direct inguinal hernia. METHODS: In 15 patients with primary bilateral direct inguinal hernia who underwent a Stoppa open posterior inguinal hernia repair, tissue specimens from the abdominal wall surrounding a direct hernia border were excised for histological examination. These findings in patients with direct inguinal hernia were compared with tissue specimens excised from the fossa inguinalis media of cadavers without hernia. RESULTS: Significant degenerative modifications such as fibrohyaline degeneration and fatty substitution of…

AdultMaleHyaline Muscular dystrophymedicine.medical_specialtyPathologyEtiologyFibrosiBiopsyHernia InguinalInflammationDirectAbdominal wallBiopsymedicineHumansHerniaNerve degenerationDirect Inguinal HerniaMuscle SkeletalInguinal hernia; Direct; Etiology; Inflammation; Muscles; Fibrosis; Hyaline Muscular dystrophy; Nerve degenerationHyalineAgedGroinmedicine.diagnostic_testbusiness.industryAbdominal WallInguinal herniaDystrophyMiddle Agedmedicine.diseaseFibrosisSurgerySettore MED/18 - Chirurgia Generalestomatognathic diseasesInguinal herniamedicine.anatomical_structureCase-Control StudiesMuscleSurgeryAtrophybusinessHernia
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